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| トップ ＞ 研究業績 |
| Togari, A., Arai, M., Kondo, H., Kodama, D., Niwa, Y. : The neuro-osteogenic network : the sympathetic regulation of bone resorption. Japanese Dental Science Review, 48 (2) : 61-70, 2012. |
| 戸苅彰史：末梢神経系と骨代謝の関わり. CLINICAL CALCIUM, 20(12)：1-8, 2010． |
| 戸苅彰史，新井通次：交感神経系を介したニューロペプチドYによる骨吸収（骨溶解）の阻害．生体の科学，60(5) : 484-485, 2009． |
| Togari, A. and Arai, M. : Pharmacological topics of bone metabolism : the
physiological function of the sympathetic nervous system in modulating
bone resorption．Journal Pharmacological Sciences, 106 : 542-546, 2008. |
| 戸苅彰史：交感神経系による骨代謝制御について. 愛知学院大学歯学会誌，46(1)1-13, 2008. |
| 小畑孝二，戸苅彰史：骨関連細胞と神経細胞の共培養実験法の確立と細胞間相互作用の検討. 口腔組織培養学会誌，17(2)15-25, 2008． |
| 戸苅彰史:交感神経活動による骨吸収の促進. CLINICAL CALCIUM，16(2) : 74-79, 2006. |
| Togari, A., Arai, M. and Kondo, A. : The role of the sympathetic nervous
system in controlling bone metabolism．Expert Opinion on Therapeutic Targets,
9(5) : 931-940, 2005. |
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| Kondo, M., Kondo, H., Miyazawa, K., Goto, S., Togari,
A. : Experimental tooth movement-induced osteoclast activation is regulated by
sympathetic signaling. Bone, 52 : 39-47, 2013. |
| Kondo, H., Takeuchi, S., Togari, A. : β-Adrenergic signaling directly stimulates
osteoclastogenesis via reactive oxygen species. American Journal of Physiology-Endocrinology
and Metabolism, 304 : E507-E-515, 2013. |
| Arai, M., Sato, T., Takeuchi, S., Goto, S., Togari, A. : Butoxamine, a
selective β2-adrenergic antagonist, prevents bone loss and fragility in
spontaneously hypertensive rat (SHR). European Journal of Pharmacology,
701 : 7-13, 2013. |
| Kodama, D., Togari, A. : Noradrenaline stimulate cell proliferation by
suppressing potassium channels via Gi/o-protein coupled α-1B-adrenergic
receptor in human osteoblast. British Journal of Pharmacology, 168 : 1230-1239,
2013. |
| Takeuchi, S., Hirukawa, K. And Togari, A. : Acidosis inhibits mineralization
in human osteoblasts. Calcified Tissues International, 93 : 233-240, 2013. |
| Kodama, D. and Togari, A. : Store-operated calcium entry induced by activation
of Gq-coupled alpha1B adrenergic receptor in human osteoblast.Biochemical
and Biophysical Research Communications, 437 : 239-244, 2013. |
| Komoto, S., Kondo, H., Fukuta, O., Togari, A. : Comparison of β-adrenergic
and glucocorticoid siganling on clock gene and osteoblast-related gene
expressions in human osteoblast. Chronobiology International, 29 : 66-74,
2012. |
| Kondo, H., Togari, A. : Continuous treatment with a low dose β-agonist
reduces bone mass by increasing bone resorption without suppressing bone
formation. Calcified Tissue International, 88 : 23-32, 2011. |
| Tsunashima, Y., Kondo, A., Matsuda, T., Togari, A. :
Hydrocortisone inhibits cellular proliferation by downregulating hepatocyte
growth factor synthesis in human osteoblasts. Biological & Pharmaceutical
Bulletin, 34 : 700-703, 2011. |
| Nagasawa, T., Arai, M., Togari, A. : Inhibitory effect of minocycline on
osteoclastogenesis in mouse bone marrow cells. Archives of Oral Biology,
56 : 924-931, 2011. |
| Suzuki, Y., Kodama, D., Goto, S., Togari, A. : Involvement of TRP channels
in the signal transduction of bradykinin in human osteoblasts. Biochemical
and Biophysical Research Communications, 410 : 317-321, 2011. |
| Kawamura, H., Arai, M., Togari, A. : Inhibitory effect of chlorpromazine
on RANKL-induced osteoclastogenesis in mouse bone marrow cells. Journal
of Pharmacological Sciences, 117 : 54-62, 2011． |
| Suga, S., Goto, S., Togari, A. : Direct neurite-osteoclastic cell communication
in vitro occurs via the adrenergic receptor. Journal of Pharmacological
Sciences, 112(2) : 184-191, 2010. |
| Matsuda, T., Kondo, A., Tsunashima, Y., Togari, A. : Inhibitory effect
of vitamin K2 on IL-1β-stimulated proliferation of human osteoblasts. Biological &
Pharmaceutical Bulletin, 33(5) : 804-808, 2010. |
| Ding, Y., Arai, M., Kondo, H., Togari, A. : Effects of capsaicin-induced
sensory denervation on bone metabolism in adult rats. Bone, 46(6) : 1591-1596,
2010. |
| Sato, T., Arai, M., Goto, S., Togari, A. : Effects of propranolol on bone
metabolism in spontaneously hypertensive rats. The Journal of Pharmacology
and Experimental Therapeutics, 334(1) : 99-105, 2010． |
Kodama, D., Togari, A. : Modulation of potassium channels via the α1B
-adrenergic receptor in human osteoblasts. Neuroscience Letters, 485 :
102-106, 2010． |
| Nishii, N., Arai, M., Yanai, N., Togari, A., Nakabayashi, T. : Effect of
bone morphogenetic protein-2 (BMP-2) or troglitazone, as an inducer of
osteogenic cells or adipocytes, on differentiation of a bone marrow mesenchymal
progenitor cell line established from temperature-sensitive (ts) simian
virus (SV) 40 T-antigen gene transgenic mice. Biological & Pharmceutical
Bulletin, 32(1) : 10-17, 2009． |
| Aki, Y., Kondo, A., Nakamura, H., Togari, A. : Lysophosphatidic acid-stimulated
interleukin-6 and-8 synthesis through LPA1 receptors on human osteoblasts. Archives of Oral Biology, 53 : 207-213,
2008. |
| Hirukawa, K., Muraki, K., Ohya, S., Imaizumi, Y. and Togari, A. : Electrophysiological
properties of a novel Ca2+ ‐activated K+ channel expressed in human osteoblasts. Calcified Tissue International,
83 : 222-229, 2008. |
| Arai, M., Kawamura, H., Mizutani, S., Togari, A. : Inhibitory effect of
sodium fluoride on expression of vitamin D receptor mRNA in mouse osteoblastic
cells. Dentistry in Japan, 43 : 33-36, 2007. |
| Amano, S., Arai, M., Goto, S., Togari, A. : Inhibitory effect of NPY on
isoprenaline-induced osteoclastogenesis in mouse bone marrow cells. Biochimica
et Biophysica Acta, 1770 : 966-973, 2007． |
| Nishii, N., Arai, M., Togari, A., Nakabayashi, T. : Mechanical bone properties
of obese model SHR/NDmcr-Cp rats. Clinical and Experimental Pharmacology
and Physiology, 34 : S29-S30, 2007． |
| Obata, K., Furuno, T., Nakanishi, M., Togari, A. : Direct neurite- osteoblastic
cell communication, as demonstrated by use of an in vitro co-culture system. FEBS Letters, 581 : 5917-5922, 2007. |
| Wakita, T., Mogi, M., Kurita, K., Kuzushima, M., Togari, A. : Increase
in RANKL : OPG ratio in synovia of patients with temporomandibular joint
disorder. Journal of Dental Research, 85(7) : 627-632, 2006. |
| Kuzushima, M., Mogi, M., Togari, A. : Cytokine-induced nitric oxide- dependent
apoptosis in mouse osteoblastic cells : involvement of p38MAP kinase. Archives
of Oral Biology, 51 : 1048-1053, 2006. |
| Ihara, H., Hirukawa, K., Goto,S., Togari, A. :
ATP-stimulated interleukin-6 synthesis through P2Y receptors on human
osteoblasts. Biochemical and Biophysical Research Communications, 326(2) : 329-334,
2005. |
| Hirukawa, K., Miyazawa, K., Maeda, H., Kameyama, Y.,
Goto, S., Togari, A. : Effect of tensile force on the expression of IGF-I and
IGF-I receptor in the organ-cultured rat cranial suture. Archives of Oral Biology,
50(3) : 367-372, 2005. |
| Ishizuka, K., Hirukawa, K., Nakamura, H., Togari, A. : Inhibitory effect
of CGRP on osteoclast formation by mouse bone marrow cells treated with
isoproterenol. Neuroscience Letters, 379(1) : 47-51, 2005. |
| Kotake, S., Nanke, Y., Mogi, M., Kawamoto, M., Furuya, T., Yago, T., Kobashigawa,
T., Togari, A., Kamatani, N. : IFN-γ-producing human T cells directly induce
osteoclastogenesis from human monocytes via the expression of RANKL. European
Journal of Immunology, 35(11) : 3353-3363, 2005. |
| Kondo, A., Togari, A. : Activation of osteoblastic
functions by a mediator of pain, bradykinin. Biochemical Pharmacology, 68 :
1423-1431, 2004. |
| Mogi, M., Ozeki, N., Nakamura, H., Togari, A. : Dual roles for NF-κB activation
in osteoblastic cells by serum deprivation : osteoblastic apoptosis cell-cycle
arrest. Bone, 35 : 507-516, 2004. |
| Utsumi, M., Moriguchi, K., Takahasni, H., Kinoshita,
H., Togari, A., Mizutani, M., Ohno, N. : Age-related changes of the
ultrastructure in the cardiomyopathic hamster (UM-X7.1 Syrian hamster)
parathyroid gland. Histology and Histopathology, 19 : 815-821, 2004. |
| Mogi, M., Otogoto, J., Ota, N., Togari, A. : Differential expression of
RANKL and osteoprotegerin in gingival crevicular fluid of patients with
periodontitis. Journal of Dental Research, 83(2) : 166-169, 2004． |
| Hirukawa, K. Miyazawa, K., Maeda, H., Kameyama, Y., Goto, S., Togari, A.
: Osteogenesis accelerated by CHO-K1 cells transfected with the IGF-I gene.
Dentistry in Japan, 40：31-34, 2004. |
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